David Arquette as WCW World Heavyweight champion

In 2000, after filming the World Championship Wrestling (WCW) movie Ready to Rumble, Arquette was brought into WCW storylines. He made his first appearance on the April 12, 2000 episode of Thunder, sitting in the crowd before leaping into the ring to take part in a worked confrontation with Eric Bischoff and his New Blood stable. Afterwards, he formed an alliance with Chris Kanyon and then reigning WCW World Heavyweight Champion Diamond Dallas Page, and with their help, he defeated Bischoff in a singles match in the April 24 episode of Nitro. On the following episode of Thunder, Arquette teamed with Page in a match against Bischoff and Jeff Jarrett, with the stipulation that whichever man got the pin would take the championship. Arquette pinned Bischoff again in the match's finish, receiving the WCW World Heavyweight Championship in the process.

After World Wrestling Federation/World Wrestling Entertainment (WWF/WWE) purchased WCW, Arquette's championship run was listed as the top reason for the "failure" of Nitro in a list published by WWE Magazine