No, especially if you use a vaporizer. People will argue memory loss but I'm not even sure about that. My mom's husband has been smoking it for well over 20 years, literally every day, and his memory is perfect.
Just invested in one. Pissed I didn't do this sooner. I put a fucking half a gram of some bomb from the dispensary, and that sum-bitch lasts damn near an hour. Not only does it save a shit ton of weed, it's also good for the lungs, tastes tremendous as it's only THC, and it doesn't reek up the house... as much.
Yeah, but vaporizer = quality.