Doing the same as I did for Oblivion - getting the vanilla version on 360, playing as Argonian first (easiest race to play as) and as an 'evil' character. After a while I'll get the PC version and have fun with the mods, then borrow the 360 GOTY edition from a friend a few years down the line and get all the achievements with a 'good' character, difficulty set all the way up.
Can't wait, so excited I'm taking a week off work to play it solid
been replaying Oblivion to get in the mood, done everything again now except the Shivering Isles storyline. Still got time